Sex Determination and Differentiation

In humans as well as other species, there are obvious differences between males and females. Differences such as the development of a penis or vagina, muscle mass, body size, the distribution of fat and the amount of distribution of body…

The sonic hedgehog gene

The sonic hedgehog gene is the human form of the hedgehog superfamily of inductive molecules that play a role in the development of the embryo. Sonic hedgehog is necessary for the development of the front part of the brain. This signaling protein helps to establish the line that separates the right and left side of the forebrain. Sonic hedgehog also plays an important role in the formation of the eyes. During early development the cells that develop into the eye form a single structure called the eye field. The structure is found in the centre of the developing face. Sonic hedgehog signaling causes the eye field to separate into two distinct eyes (National Library of Medicine, 2020

Pharmacology basics| Drug Metabolism and Absorption.

The rate and degree of blood and absorption into the blood is dependent on the route of administration. Effective absorption from the oral route depends on both the chemical properties of the drug and the functional efficacy of the GI tract. Parenteral absorption is dependent on the extent of blood supply. The bioavailability of a drug is the most critical part of pharmacokinetics.

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