Hemostasis is a complex process that involves multiple interlinked steps. The aim of the cascade is to form a plug that closes the damaged site of the blood vessels, thereby controlling bleeding. It begins with injury in the lining of the blood vessels. The process can be split into four phases, this includes; constriction of the blood vessels, formation of the temporary platelet plug, activation of the coagulation cascade and formation of the fibrin plug or the final clot. There are numerous cells that are involved in the clotting cascade, most notably are the processes associated with the endothelium, platelets and hepatocytes (LaPelusa & Dave, 2020).