The sonic hedgehog gene

The sonic hedgehog gene is the human form of the hedgehog superfamily of inductive molecules that play a role in the development of the embryo. Sonic hedgehog is necessary for the development of the front part of the brain. This signaling protein helps to establish the line that separates the right and left side of the forebrain. Sonic hedgehog also plays an important role in the formation of the eyes. During early development the cells that develop into the eye form a single structure called the eye field. The structure is found in the centre of the developing face. Sonic hedgehog signaling causes the eye field to separate into two distinct eyes (National Library of Medicine, 2020

Pharmacology basics| Drug Metabolism and Absorption.

The rate and degree of blood and absorption into the blood is dependent on the route of administration. Effective absorption from the oral route depends on both the chemical properties of the drug and the functional efficacy of the GI tract. Parenteral absorption is dependent on the extent of blood supply. The bioavailability of a drug is the most critical part of pharmacokinetics.

Below is A list of some Common Respiratory Illnesses.

Respiratory illnesses can be divided into those of the upper and lower respiratory tract. They can further be divided into those that are caused by infectious particles like viruses, bacteria, and environmental. The upper respiratory system consists of the nasal…

Needless treatments: Psychotropics are rarely effective in ‘calming’ dementia patients

         Elderly individuals with dementia often experience several neuropsychiatric symptoms such as delusion, hallucinations, anxiety, irritability and agitation. Currently, the management of these symptoms is a combination of non- pharmacological and pharmacological interventions such as use of psychotropic drugs (PDs)…

What Makes Heroin So Addictive and Dangerous?

There are two main ways that heroin is metabolised; one of the ways is through the Hepatic First Pass. This is done via the removal of an acetyl group when taken orally. The other way is through injections. Heroin that is administered via this route will evade the Hepatic First Pass and will quickly cross the blood-brain barrier. This is because of the presence of an acetyl group that makes it more soluble to fat. Once, in the brain, the acetyl group is removed, and heroin is reduced to 3-monoacetylmorphine and 6-monoacetylmorphine.

WHY IS CALCIUM IMPORTANT

Lack of calcium in the diet can lead to osteoporosis in which the bone is less dense and therefore brittle and weak. In women, osteoporosis can be due to lack of oestrogens after menopause or oophorectomy. Calcium is usually ubiquitous in diet, but often, a small amount of food provides reasonable amounts, of which dairy products are best.

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