Between 2016-2017, there were 1.6 million emergency department visits among people over the age of 65. The three most common presentations where chest pain, and musculoskeletal issues related to falls ( Falls Resulting in Patient Harm in Hospitals, 2018). Dementia people living in residential aged care facilities are vulnerable, frail and often have many comorbidities that put them at risk of falls (Fernando et al., 2017). For many of these resident’s hospitalisation, carries it with it a lot of risks. (Bail et al., 2015) Found that urinary tract infections, pressure areas, pneumonia and delirium are preventable hospital acquired complications that place a heavy financial burden on the health care system. Studies show that while people with dementia are at higher risk of hospital readmission, many of these hospitalisations are preventable (Ma et al., 2019).
Mental health relates to any behaviours and conditions which impedes with social functioning capacity to negotiate daily life (WHO | Mental Health, 2019) . Many older people will have some sort of mental health issue at some point, this may be due to illness, grief and loss, financial stress and loss of independence. Between 2017-18, 9.9 billion dollars was spent in mental health and 4.3 million people received mental health services. Mental health is as important as physical wellbeing for elderly people, this is also true for people with dementia (Mental Health Services in Australia, Prevalence, Impact and Burden, 2019). The vulnerable group chosen for this paper is elderly people with dementia living in long term aged care homes and in the community. The national health priority in focus is mental health.
Sundowning syndrome or nocturnal delirium is used to describe a wide range of behaviours of neuropsychiatric (NPS) symptoms that often happen in people with dementia. The behavioural and neuropsychiatric symptoms seen in people with dementia and Alzheimer’s disease include; repetitive behaviours, delusions, misidentification, wandering, suicidal and sociopathic behaviours. Both normal ageing and dementia are associated with changes to the circadian regulation of physiology and behaviour (Cipriani et al., 2015)
Between 2017-18, 9.9 billion dollars was spent in mental health and 4.3 million people received mental health services (Mental Health Services in Australia, Prevalence, Impact and Burden, 2019). The proportion of older Australians is increasing and so as the life expectancy, which means an overall increase in chronic illnesses. The prevalence for dementia in Aboriginal and Torres Islander communities is 2 -5 times higher than that of non-Aboriginal Australians (The Health and Welfare of Australia’s Aboriginal and Torres Strait Islander Peoples, 2015). There several factors that are said to contribute to this disturbing trend. For example, Aboriginal and Torres strait Islanders, tend to have double the rates of traumatic injury, higher rates of smoking and have a markedly higher incidence of chronic illnesses such as diabetes, cardiovascular and renal diseases
Cocaine is a psychoactive alkaloid of the coca plant; it was originally used for local surgeries as an anaesthetic but has now become a recreational drug. Unlike amphetamines, which resemble the structural formula of dopamine and noradrenaline, cocaine has a similar structure to other synthetic sedatives. Cocaine is well absorbed when administered via the mucous membranes, the GI tract and IV route. Peak concentration happens within five minutes after intravenous injection, while the peak levels from smoking are usually reached within 60 minutes. Some cocaine is excreted in urine unchanged, the majority is metabolised into benzoylecgonine, ecgonine methyl ester, norcocaine and other metabolites. Although cocaine has a short half-life, the elimination half-life of the metabolites lasts longer. Studies also show that the half-life of cocaine may increase the longer it is used.
Hemostasis is a complex process that involves multiple interlinked steps. The aim of the cascade is to form a plug that closes the damaged site of the blood vessels, thereby controlling bleeding. It begins with injury in the lining of the blood vessels. The process can be split into four phases, this includes; constriction of the blood vessels, formation of the temporary platelet plug, activation of the coagulation cascade and formation of the fibrin plug or the final clot. There are numerous cells that are involved in the clotting cascade, most notably are the processes associated with the endothelium, platelets and hepatocytes (LaPelusa & Dave, 2020).
Over accumulation of fluid in the interstitial space is generally bad and it affects the proper function of the tissue. This is because the formation of oedema increases the diffusion distance of oxygen and other nutrients. And for the same reason it reduces the diffusional removal of potentially toxic substances of cellular metabolism. This is especially important in the lungs where pulmonary oedema can greatly affect exchange of gasses. Also, certain anatomical structures limit tissue expansion in response to oedema. For example, the kidneys, brain, and the skeletal muscles (Scallan et al., 2010a). This means that small incremental changes in transcapillary fluid filtration will induce a large increase in interstitial fluid pressure.
Inflammation is a pathological response that engages hundreds of mediators and different cells and tissue types. It can be initiated by any stimulus causing cell injury. Often the inflammation is a response to some sort of infection. In some cases, chemical or physical injury can also induce an inflammatory reaction. The goal of the inflammatory response is to remove the causative agent with minimal destruction to the body, and to repair the damage caused by the toxin. The duration of the inflammatory response is dependent on whether the causative agent has been eliminated. Acute inflammation is a relatively short process, lasting from minutes to a few day
Palliative care can be defined as an approach to health that involves improving the quality of life of patients and their families that are facing issues related to chronic, incurable and life-threatening illnesses (Wallerstedt et al., 2019). It is vital to note that, palliative care is not just limited to the elderly, but can be anyone with an incurable illness and the goal is to improve quality of life. The stages of palliative care include; stable, unstable, deteriorating, terminal and bereavement (McClelland et al., 2020).
According to World Vision, the most alarming statistic about child marriage is that almost 700 million women in the world today were married as girls. A third of them before there 15th birthday. Child marriage is a legal marriage or informal union where one or both parties are under the age of 18.
The sonic hedgehog gene is the human form of the hedgehog superfamily of inductive molecules that play a role in the development of the embryo. Sonic hedgehog is necessary for the development of the front part of the brain. This signaling protein helps to establish the line that separates the right and left side of the forebrain. Sonic hedgehog also plays an important role in the formation of the eyes. During early development the cells that develop into the eye form a single structure called the eye field. The structure is found in the centre of the developing face. Sonic hedgehog signaling causes the eye field to separate into two distinct eyes (National Library of Medicine, 2020
The rate and degree of blood and absorption into the blood is dependent on the route of administration. Effective absorption from the oral route depends on both the chemical properties of the drug and the functional efficacy of the GI tract. Parenteral absorption is dependent on the extent of blood supply. The bioavailability of a drug is the most critical part of pharmacokinetics.
Today there is an alarming trend in some countries where the procedure is being carried out by health care providers. UNICEF estimates that one in four FGM procedures where performed by a health care personnel. Medicalising this procedure risks normalising it and just because a doctor does it does not make it any less barbaric.
There are two main ways that heroin is metabolised; one of the ways is through the Hepatic First Pass. This is done via the removal of an acetyl group when taken orally. The other way is through injections. Heroin that is administered via this route will evade the Hepatic First Pass and will quickly cross the blood-brain barrier. This is because of the presence of an acetyl group that makes it more soluble to fat. Once, in the brain, the acetyl group is removed, and heroin is reduced to 3-monoacetylmorphine and 6-monoacetylmorphine.
Lack of calcium in the diet can lead to osteoporosis in which the bone is less dense and therefore brittle and weak. In women, osteoporosis can be due to lack of oestrogens after menopause or oophorectomy. Calcium is usually ubiquitous in diet, but often, a small amount of food provides reasonable amounts, of which dairy products are best.
Article 27 of the fourth Geneva convention of 1949 clearly, states that women are to be protected against any attacks on their honor. Particularly against Rape, enforced prostitution or any form of indecent assault. The most vulnerable during war are the women and the children. Girls are usually raped and tortured, boys are trained as child soldiers, as is the currently the case in Congo and Somalia
The Human Immunodeficiency Virus (HIV) belongs to a family of viruses called the lentiviruses; it is a Retrovirus that causes acquired immunodeficiency syndrome (AIDS), a condition that causes the degeneration of the immune system. This leaves an individual more prone to opportunistic infections and some forms of cancers. HIV/AIDS is transmitted through the contact of infected Blood, semen, vaginal fluid and through breast milk; the most common way that HIV/AIDS is spread through sexual intercourse with an infected person. This paper will look at the history of HIV/AIDS, the distribution, how the HIV/AIDS infects the host and how it targets the immune system (Sharp & Hahn, 2011).
Palliative care is an approach to care that focuses on improving the quality of life of patients and their families facing the issues that are associated with life-threatening chronic incurable illnesses (Jarrell, 2016). It is important to note that palliative care does not mean end of life care and patients can be on palliative for years before they die (Wallerstedt et al.,